Building a golden triangle for the production and use of artemisinin derivatives against falciparum malaria in Africa
نویسندگان
چکیده
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria. Molecular Bio/Sciences Limited, 124 MCC Road, Calabar, Nigeria. Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Nigeria. Chemical, Biological and Agricultural Pluridisciplinary Research Center (CPQBA), University of Campinas, Campinas, SP, Brazil. USDA, ARS, Appalachian Farming System Research Center, 1224 Airport Road, Beaver, West Virginia 25813, USA
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Natural product-derived drugs exemplified by quinine, isolated from South American Cinchona species and artemisinin discovered in China are of immense importance for the treatment of malaria. Although malaria parasites resistant to artemisinin have not yet been found in malaria patients, the need for new antimalarial agents remains. The burden of malaria is heaviest in Africa where over a milli...
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